What's Wrong? is a Flash screamer. Its earliest version was found in 2001. The animation starts with a still picture of a dining room. After about 30 seconds, a black and white picture of a woman with large black eyes, a wide open mouth and her hands on her face from the 2001 movie Maniacts, briefly appears accompanied by a male scream. The animation then repeats.
Being reuploaded on multiple websites like YouTube, this animation has gained many views. Screamers of this kind became more and more popular as they began to circulate on the Internet. A few more examples of this are What's wrong with this picture? and Zoeken.
NOTE: The following animation contains a screamer.